153 Therapeutics

153 Therapeutics153 Therapeutics153 Therapeutics153 Therapeutics

Advancing treatments for neurodegeneration.

153 Therapeutics

153 Therapeutics153 Therapeutics153 Therapeutics153 Therapeutics

Advancing treatments for neurodegeneration.

About Us

Our Mission

Our Mission

Our Mission

 We are focused on developing novel, best-in-class therapeutics for central nervous system (CNS) disorders such as Parkinson’s Disease, Alzheimer’s Disease and ALS, among others. Our unique approach targets nuclear receptors in the brain to regulate transcriptional activity and restore normal signaling and function. Pre-clinical progress 

 We are focused on developing novel, best-in-class therapeutics for central nervous system (CNS) disorders such as Parkinson’s Disease, Alzheimer’s Disease and ALS, among others. Our unique approach targets nuclear receptors in the brain to regulate transcriptional activity and restore normal signaling and function. Pre-clinical progress to date demonstrates the potential for this approach to yield better therapies for patients.

Our History

Our Mission

Our Mission

 Our founding team is from the University of California at San Francisco (UCSF), one of the top neuroscience research institutions in the US. With a successful basic research program funded in part by the NIH and the Michael J. Fox Foundation, the company was spun out and has exclusive licensing rights from UCSF. The founding team has dec

 Our founding team is from the University of California at San Francisco (UCSF), one of the top neuroscience research institutions in the US. With a successful basic research program funded in part by the NIH and the Michael J. Fox Foundation, the company was spun out and has exclusive licensing rights from UCSF. The founding team has decades of experience in discovering, developing and bringing new drugs to market.

Our Team

Our Mission

Our Team

Pamela M. England, PhD

Co-Founder


Peter Noymer, PhD

CEO and Co-Founder


Matthew P. Jacobson, PhD

Co-Founder

Contact Us

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